How to proceed with CSIR-NET Immunology Section in Brief
Dr. Jatin Mehta
(National Institute of
Immunology, Delhi)
In the present report, we are
presenting trend analysis of the Immunology Section. As are aware, Immunology
in itself is a challenging subject and often demands graspand clarity over
basic concepts. Though it is presented as a part of Cellular Communication
section in the syllabus, but often recommended to prepare as an independent
knowledge domain. Generally 3-5 questions
are asked each year from this portion.
Since it is a vast subject,
hence one should judiciously know how to manage time among important topics
from exam point of view. Presented here the detailed trend analysis based on
the past year question papers. Remember this analysis is suggestive only and
designed to galvanize you for maximum reward.
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Jun-11
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Dec-11
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Jun-12
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Dec-12
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Jun-13
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Dec-13
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Jun-14
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Dec-14
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Jun-15
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Dec-15
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Jun-16
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Dec-16
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Jun-17
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Dec-17
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Immune System and its components,
Immunity types,
Immune Response
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1
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1
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Antigens, Haptens
and Epitopes.
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1
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1
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Antibodies:
Structure & functions,Isotype,
Allotype, Idiotype, Immune response
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1
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1
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1
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1
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1
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2
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T and B cell maturation
and proliferation and
activation.
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1
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1
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1
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1
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1
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1
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1
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Microbial
Infection,Toll like receptors (TLR)
& Complement System
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1
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1
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1
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1
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1
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1
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1
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Cytokines
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2
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1
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3
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1
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1
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1
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1
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Ag-Ab interaction,
ImmunoMethods
(ELISA, RIA, FACS, MAB,
Antibody Generation, Antibody Therapy
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2
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1
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1
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1
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4
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1
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1
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1
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1
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1
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Vaccines – Important, types of immunization,
live
and killed vaccines, toxoids etc.
conjugate vaccine, DNA vaccine
and RDT
vaccines are more imp.
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1
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1
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1
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1
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2
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1
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1
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MHC and its role
in Graft rejection,
Transplantation & its Types
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1
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1
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1
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1
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1
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Immunodeficiency and
Hypersensitivity
Reactions
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1
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1
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1
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TOPIC WISE ANALYSIS OF
IMMUNOLOGY SECTION
SNo
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TOPICS
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ANALYSIS
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1
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Cells and Organs of Immune System
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Just study
basics, as no questions asked.
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2
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Types of immunity- innate and
adaptive and its components
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This area lays
the foundation of immunology, some basic questions could be asked in
part-B.Toll like receptorsis important and the connection between innate
and adaptive immunity.
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3
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Antigens
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Basic
terminology of different antigens. Terms like haptens and epitopes.
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4
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Antibodies: Structure, Function
and Diversity
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Study structure
in detail, their types and functions, differentiate between terms like
isotype, allotype, idiotype. - Some basic question could be asked in part-B.
Just cover the basic reasons for Ab diversity, don’t lay much emphasis on
detailed mechanisms as not very important.
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5
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Cytokines
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It
is very important, their families and functions, different cytokines involved
in innate and adaptive immunity, cytokines in therapy is important –
Questions consistently asked in Part-C.
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6
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Immunological Methods
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Antigen
– antibody interaction – important as questions
asked, specially Part-C, some analysis required….areas important
can be Elisa and its variants, RIA, flow cytometary, monoclonal and
polyclonal Ab. – Generation of monoclonal Ab. Purification and uses, Ab
therapy is imp.
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7
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Hypersensitivity Reactions
Immunodeficiency, Auto-immunity and autoimmune diseases
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Important, types
of hypersensitivity reaction and their role in disease development e.g.
asthma, hay fever etc.
Study just the
basics of immunodeficiency, autoimmunity, lay more emphasis on diseases.
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8
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Vaccines
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Important, types
of immunization, can leave designing of vaccines, lay emphasis on types of
vaccines e.g. live and killed vaccines, toxoids etc. conjugate vaccine, DNA
vaccine and RDT vaccines are more imp.
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9.
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Transplantation
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Very
important, questions asked, transplantation types, graft rejection, cells
involved in graft rejection, immunosuppressive therapy and drugs used in it
is important, clinical transplantation- questions asked on liver transplant.
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10
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T and B cell maturation and
proliferation and activation.
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Just
cover basics of B and T cells proliferation upon activation. Read about
specific CDs expressed on different types of B and T cells.
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11
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OTHER
AREAS TO BE COVERED
a) Complement System
b) MHC
c) Antigen processing and presentation – can
lay little emphasis if time allows.
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